top of page

Migraines and Light Sensitivity

Migraines are a health condition and are more than just a bad headache. Migraine symptoms are different from person to person but often include headaches that keep coming back, nausea, vomiting, changes in mood, extreme tiredness, and sensitivity to light, noise, and smells.

Newest Technology Available to Patients

Avulux’s physicians and engineers designed a lens that filters up to 97% of harmful blue, amber, and red light, all while allowing soothing green light in.

How does the Avalux lens work?

The Arunalight looks like a pair of sunglasses and is worn for 3 minutes every other day at home. A total of 26 red lights are strategically placed to gently treat the eyes and surrounding skin. With a lifespan for thousands of uses, these medical grade light diodes offer a superior defined and optimized wavelength (670nm).

What is the difference between Avalux and other products on the market?

Photobiomodulation has shown great promise in treating various retinal conditions. A study by Benlahbib et al. (2023) suggests that photobiomodulation may offer a viable therapeutic option for age-related macular degeneration, potentially slowing the progression of the disease. Additionally, another study demonstrated a significant reduction in the onset of new geographic atrophy in patients receiving photobiomodulation treatment. 

Additional studies show promising results for photobiomodulation in treating diabetic retinopathy, including reducing macular edema and improving visual acuity. In glaucoma, PBM may help enhance retinal nerve fiber layer thickness and lower intraocular pressure. For dry eye syndrome, it has the potential to increase tear production and improve meibomian gland function. PBM also shows promise in reducing inflammation in uveitis and other inflammatory ocular conditions. While most studies to date have been conducted in animal models, the findings are promising, and while applications to humans are still limited, they remain a potential avenue for future exploration.

Benlahbib, M., Cohen, S. Y., Torrell, N., Colantuono, D., Crincoli, E., Amoroso, F., Semoun, O., Jung, C., and Souied, E. H. (2023) ‘Photobiomodulation Therapy for Large Soft Drusen and Drusenoid Pigment Epithelial Detachment in Age-Related Macular Degeneration: A Single-Center Prospective Pilot Study’, Retina, 43(8), pp.1246-1254. Available at: https://doi.org/10.1097/IAE.0000000000003805

Some studies involving Cellular Mechanisms activated with Photobiomodulation at 670nm

Oxidative Stress Reduction in Diabetic Retinopathy

This wavelength ameliorates diabetic retinopathy by reducing oxidative stress and cell death, offering a potential therapeutic approach for diabetic retinopathy management.

Müller Cell-Mediated Retinal Inflammation Reduction

670 nm light reduces Müller cell-mediated
retinal inflammation, which could be beneficial in treating retinal degenerations associated with inflammation.

Improved Retinal Function in Aging

670 nm light can significantly improve aged retinal function, potentially providing benefits in age-related visual impairments.

Optic Nerve Protection

NIR-LED photobiomodulation accelerates wound healing and attenuates degeneration in the injured optic nerve, suggesting its potential use in optic nerve injuries or
degenerative diseases.

Photoreceptor Neuroprotection

The light therapy increases the spare respiratory capacity of mitochondria in photoreceptor-like cells, which can prevent photoreceptor cell death in conditions
like age-related macular degeneration.

Inhibition of Diabetic Retinopathy Progression

The light inhibits the functional and histopathologic features of early diabetic retinopathy, likely mediated via multiple mechanisms, offering a potential
therapeutic approach for diabetic retinopathy management.

Cell Viability Improvement

670 nm LED irradiation enhances cell viability in hypoxic rhesus monkey choroid-retinal cells.

Mitochondrial Function Augmentation

Red light promotes mitochondrial function and stimulates antioxidant pathways, protecting photoreceptors in retinal dystrophy and potentially aiding in diseases like retinitis pigmentosa.

Reduction in Retinal Inflammation

The light improves mitochondrial metabolism, reducing retinal inflammation, which could be useful in managing inflammatory retinal diseases.

Therapy for Large Soft Drusen

PBM may provide a valid therapeutic option for large soft drusen and drusenoid pigment epithelial detachment age-related macular degeneration and may potentially slow the natural course of the disease.

Improved clinical and anatomical outcomes for Dry AMD

Improvements in clinical and anatomical endpoints following PBM treatment suggest disease-modifying effects.

Improvement in Scotopic Thresholds

In healthy ageing, rod function and scotopic thresholds appear to improve by 12 months with 670 nm light.

Introducing
Avalux!

Avulux Migraine & Light Sensitivity Lenses are the only clinically proven lenses that precisely filter light to help people living with migraine.

avalux_edited.png
neurons_edited_edited_edited.jpg

What are
Migraines?

Migraine is an extremely disabling, common neurological disorder characterized by a complex neurobiology, involving a series of central and peripheral nervous system areas and networks. The underlying feature seems to be a, probably complex, genetic predisposition combined with behavioral and environmental conditions that causes an alteration of sensory brain processing, resulting in increased sensory susceptibility.

Migraine is characterized by a succession of key phases that often overlap: the premonitory (prodromal), aura, pain and postdromal phases. Better recognition of these events has allowed us to conceptualize migraine as a network disorder involving multiple cortical, subcortical and brainstem regions, generating a wide constellation of signs and symptoms.

brain_edited.png

Findings in vitro and in vivo support the hypothesis that photobiomodulation (PBM) enhances mitochondrial function and activates antioxidant pathways in the neural retina, protecting against retinal degeneration. PBM offers a non-invasive alternative to traditional treatments, harnessing the body's natural repair mechanisms to prevent and treat retinal dystrophies and degenerative diseases.

Recent data indicate that 670nm red light significantly protects the retina from light-induced damage, suggesting its potential to mitigate the harmful effects of bright light exposure. This non-invasive approach shows promise for treating retinal degenerative disorders and ocular inflammatory diseases.

The effectiveness of PBM depends on factors such as light source, wavelength, energy density, light pulse structure, and application duration.

bottom of page